ODCs

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4 OMIM references -
3 associated genes
No signs/symptoms info

PROTEIN INTERACTIONS: 1

1 OMIM reference -
1 associated gene
6 signs/symptoms

Dowling-Degos disease

Naegeli-Franceschetti-Jadassohn syndrome


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	KRT5	(0.69)	KRT14

Citations in the biomedical literature:

Dowling-Degos disease		Naegeli-Franceschetti-Jadassohn syndrome
	Synonym(s): - Reticular pigment anomaly of flexures		Synonym(s): - NFJ syndrome - Naegeli syndrome

	Classification (Orphanet): - Inborn errors of metabolism - Rare genetic disease - Rare skin disease		Classification (Orphanet): - Rare developmental defect during embryogenesis - Rare genetic disease - Rare skin disease

	Classification (ICD10): - Diseases of the skin and subcutaneous tissue -		Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -

	Epidemiological data: Class of prevalence: unknown Average age onset: adolescence / young Average age of death: normal Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: neonatal/infancy Average age of death: any age Type of inheritance: autosomal dominant

	External references: 4 OMIM references - No MeSH references		External references: 1 OMIM reference - No MeSH references

Naegeli-Franceschetti-Jadassohn syndrome
	Very frequent - Autosomal dominant inheritance - Dysplastic / thick / grooved fingernails - Dysplastic / thick / grooved toenails - Enamel anomaly - Irregular / in bands / reticular skin hyperpigmentation - Palmoplantar hyperkeratosis / keratoderma
Dowling-Degos disease
(no data available)